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KMID : 1130320150580080301
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Korean Journal of Pediatrics
2015 Volume.58 No. 8 p.301 ~ p.308
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Evaluation of three glucometers for whole blood glucose measurements at the point of care in preterm or low-birth-weight infants
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Hwang Joon-Ho
Sohn Yong-Hak
Chang Seong-Sil
Kim Seung-Yeon
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Abstract
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Purpose: We evaluated three blood glucose self-monitoring for measuring whole blood glucose levels in preterm and low-birth-weight infants.
Methods: Between December 1, 2012 and March 31, 2013, 230 blood samples were collected from 50 newborns, who weighed, ≤2,300 g or were ≤36 weeks old, in the the neonatal intensive care unit of Eulji University Hospital. Three blood glucose self-monitoring (A: Precision Pcx, Abbott; B: One-Touch Verio, Johnson & Johnson; C: LifeScan SureStep Flexx, Johnson & Johnson) were used for the blood glucose measurements. The results were compared to those obtained using laboratory equipment (D: Advia chemical analyzer, Siemens Healthcare Diagnostics Inc.).
Results: The correlation coefficients between laboratory equipment and the three blood glucose self-monitoring (A, B, and C) were found to be 0.888, 0.884, and 0.900, respectively. For glucose levels≤60 mg/dL, the correlation coefficients were 0.674, 0.687, and 0.679, respectively. For glucose levels>60 mg/dL, the correlation coefficients were 0.822, 0.819, and 0.839, respectively. All correlation coefficients were statistically significant. And the values from the blood glucose selfmonitoring were not significantly different from the value of the laboratory equipment , after correcting for each device’s average value (P>0.05). When using laboratory equipment (blood glucose ≤60 mg/ dL), each device had a sensitivity of 0.458, 0.604, and 0.688 and a specificity of 0.995, 0.989, and 0.989, respectively.
Conclusion: Significant difference is not found between three blood glucose self-monitoring and laboratory equipment. But correlation between the measured values from blood glucose self-monitoring and laboratory equipment is lower in preterm or low-birth-weight infants than adults.
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KEYWORD
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Preterm, Low-birth-weight infant, Blood glucose self-monitoring, Hypoglycemia
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